Chromosomal abnormalities and psychosis

Br J Psychiatry. 2006 Jun:188:501-3. doi: 10.1192/bjp.bp.106.023895.

Abstract

The search for susceptibility genes for schizophrenia and severe affective disorder has been enhanced by the study of cytogenetic abnormalities that disrupt genes directly. One such gene is DISCI and there is increasing evidence that it may be an important modulator of risk of psychosis.

Publication types

  • Editorial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chromosome Aberrations*
  • Genetic Predisposition to Disease
  • Humans
  • Nerve Tissue Proteins / genetics
  • Psychotic Disorders / genetics*
  • Schizophrenia / genetics

Substances

  • DISC1 protein, human
  • Nerve Tissue Proteins