Rupture of infective endocarditis-associated perivalvular abscess of left ventricular outlet leading to death is a rare complication of transesophageal echocardiography. We report a case of impending rupture periaortic valve abscess of left ventricular outlet that was initially diagnosed as acute pericarditis at the emergency department in which the patient suddenly collapsed during the ongoing procedure of transesophageal echocardiography. Emergency surgical intervention was performed, but in vain. Destructive aortic valve and rupture of the periaortic valve abscess were found.