In vitro activity of sodium benzoate against clinically relevant Enterococcus faecalis and Enterococcus faecium isolates

J Microbiol. 2006 Feb;44(1):129-31.

Abstract

The antimicrobial effects of sodium benzoate against Enterococcus faecalis and Enterococcus faecium were investigated. The MIC(90) of sodium benzoate were 64 mg/L for E. faecalis and 32 mg/L for E. faecium, while the MBC(90) were 128 mg/L and 64 mg/L, respectively. Although further studies are required for clinical evidence, sodium benzoate seems to be effective against Enterococcus spp.

MeSH terms

  • Enterococcus faecalis / drug effects*
  • Enterococcus faecalis / isolation & purification
  • Enterococcus faecium / drug effects*
  • Enterococcus faecium / isolation & purification
  • Humans
  • Microbial Sensitivity Tests / methods
  • Sodium Benzoate / pharmacology*

Substances

  • Sodium Benzoate