The level of prepulse inhibition in healthy individuals may index cortical modulation of early information processing

Stella G Giakoumaki; Panos Bitsios; Sophia Frangou

doi:10.1016/j.brainres.2006.01.056

The level of prepulse inhibition in healthy individuals may index cortical modulation of early information processing

Brain Res. 2006 Mar 17;1078(1):168-70. doi: 10.1016/j.brainres.2006.01.056. Epub 2006 Feb 21.

Authors

Stella G Giakoumaki¹, Panos Bitsios, Sophia Frangou

Affiliation

¹ Department of Psychiatry and Behavioural Sciences, Medical School, University of Crete, Heraklion 71003, Crete, Greece.

PMID: 16492380
DOI: 10.1016/j.brainres.2006.01.056

Abstract

This study examined whether baseline PPI levels reflect individual efficiency in tasks associated with routine versus supervisory attentional systems (SAS). PPI and neuropsychological data were collected from 30 healthy male subjects. High PPI was associated with shorter movement times on the 5-choice Reaction Time and shorter Subsequent Thinking Times in the Stockings of Cambridge test. These data suggest that high-PPI status reflects greater efficiency in tasks that engage SAS.

Publication types

Comparative Study

MeSH terms

Acoustic Stimulation / methods
Adult
Attention / physiology
Cerebral Cortex / physiology*
Choice Behavior / physiology
Humans
Male
Mental Processes / physiology*
Neural Inhibition / physiology*
Reaction Time / physiology*
Reflex, Startle / physiology
Time Factors