Oscillations, intercellular coupling, and insulin secretion in pancreatic beta cells

PLoS Biol. 2006 Feb;4(2):e49. doi: 10.1371/journal.pbio.0040049. Epub 2006 Feb 14.

Abstract

Insulin is a potent metabolic regulator that is released by pancreatic beta-cells, which respond to body glucose concentrations. Here the authors explain the physiological basis of insulin release.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenosine Triphosphate / biosynthesis
  • Animals
  • Calcium Signaling*
  • Cell Communication
  • Glucose / metabolism
  • Humans
  • Insulin / metabolism*
  • Insulin Secretion
  • Islets of Langerhans / cytology*
  • Islets of Langerhans / metabolism*

Substances

  • Insulin
  • Adenosine Triphosphate
  • Glucose