Role of stress and sympathetic innervation in the development of polycystic ovary syndrome

Endocrine. 2005 Dec;28(3):319-24. doi: 10.1385/ENDO:28:3:319.

Abstract

This article presents a review of the role of the sympathetic activity in ovarian pathologies affecting reproductive function. We provide a succinct outline of the findings of our group in this area. The participation of stress as an etiological factor for ovarian pathologies throughout animal models and data in patients with polycystic ovary syndrome give strong support for participation of sympathetic nerves in the ovary function both in normal and pathological status.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Female
  • Haplorhini
  • Humans
  • Ovarian Follicle / innervation
  • Ovarian Follicle / physiopathology
  • Ovary / innervation*
  • Ovary / physiopathology
  • Polycystic Ovary Syndrome / etiology
  • Polycystic Ovary Syndrome / physiopathology*
  • Rats
  • Receptors, Adrenergic, beta / physiology*
  • Stress, Psychological / complications*
  • Stress, Psychological / physiopathology
  • Sympathetic Fibers, Postganglionic / physiopathology
  • Sympathetic Nervous System / cytology
  • Sympathetic Nervous System / physiopathology*

Substances

  • Receptors, Adrenergic, beta