Iatrogenic Mycobacterium abscessus infection associated with acupuncture: clinical manifestations and its treatment

Int J Dermatol. 2005 Oct;44(10):846-50. doi: 10.1111/j.1365-4632.2005.02241.x.

Abstract

Background: Mycobacterial infections transmitted by acupuncture are an emerging problem. There have been two reports of mycobacterial infections complicating acupuncture in the English literature.

Aim: To describe the clinical manifestations and treatment of patients who acquired localized Mycobacterium abscessus infection in the process of acupuncture.

Methods: Clinical manifestations and responses to different methods of treatment were reviewed in 40 patients who developed various skin lesions after acupuncture at a Korean oriental medicine clinic. Results The morphology of the lesions which developed at the acupuncture sites varied. Although the lesions disappeared with the combined administration of clarithromycin and amikacin for 3 months in most cases, five out of 25 patients (20%) showed residual lesions at the end of treatment, and had to be treated with a higher dosage of clarithromycin or alternative antibiotics based on sensitivity tests.

Conclusions: We recommend at least 3 months of treatment with clarithromycin for treating skin infections caused by M. abscessus, with supplementary antibiotics selected based on patients' drug sensitivity tests.

Publication types

  • Comparative Study

MeSH terms

  • Acupuncture Therapy / adverse effects*
  • Adult
  • Amikacin / therapeutic use
  • Anti-Bacterial Agents / therapeutic use
  • Clarithromycin / therapeutic use
  • Female
  • Humans
  • Iatrogenic Disease
  • Male
  • Middle Aged
  • Mycobacterium Infections, Nontuberculous / drug therapy
  • Mycobacterium Infections, Nontuberculous / etiology*
  • Mycobacterium Infections, Nontuberculous / pathology
  • Skin / drug effects
  • Skin / pathology
  • Skin Diseases, Bacterial / drug therapy
  • Skin Diseases, Bacterial / etiology*
  • Skin Diseases, Bacterial / pathology
  • Time Factors
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents
  • Amikacin
  • Clarithromycin