Cutaneous melanoma in Swedish women: Occupational risks by anatomic site

Am J Ind Med. 2005 Oct;48(4):270-81. doi: 10.1002/ajim.20212.

Abstract

Background: Few occupational studies have addressed melanoma in women. Accordingly, our aim was to identify occupations with higher risk of cutaneous melanoma, overall and by site, in Swedish female workers.

Methods: All gainfully employed Swedish women were followed-up from 1971 to 1989, using Death/Cancer Registers. Occupational risk ratios adjusted for age, period, town size, and geographic zone were computed for each site. Risk patterns for different sites were then compared.

Results: High risks were observed among educators, bank tellers, dental nurses, librarians/archivists/curators, horticultural workers, and hatmakers/milliners. Telephone operators and textile workers had increased risk, mainly in the leg. Other occupation-specific site excesses were also found. Upper-limb risks were correlated with head/neck and thorax, though these two sites were not associated. Legs registered a special pattern, with a moderate correlation with upper limbs or thorax, and no correlation with head/neck.

Conclusions: Some occupations with possible exposure to arsenic/mercury displayed increased risk. The generalized excess risk among hatmakers/milliners warrants further attention. The weak correlation between legs and other sites suggests site specificity in melanoma risk factors.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Arsenic / toxicity
  • Female
  • Humans
  • Melanoma / chemically induced
  • Melanoma / epidemiology*
  • Mercury / toxicity
  • Middle Aged
  • Occupational Diseases / chemically induced
  • Occupational Diseases / epidemiology*
  • Registries
  • Risk Assessment
  • Risk Factors
  • Skin Neoplasms / chemically induced
  • Skin Neoplasms / classification
  • Skin Neoplasms / epidemiology*
  • Sweden / epidemiology

Substances

  • Mercury
  • Arsenic