[Rash and nephrotic syndrome: consider syphilis]

Presse Med. 2005 May 14;34(9):657. doi: 10.1016/s0755-4982(05)84007-2.
[Article in French]

Abstract

Introduction: Kidney disease is among the clinical manifestations of secondary syphilis, as this case report shows.

Observation: During serologically confirmed secondary syphilis, a 63-year-old man developed a nephrotic syndrome diagnosed after biopsy as membranous nephropathy.

Discussion: Membranous nephropathy is an immunological complication of secondary syphilis. Recovery usually follows treatment. It is often associated with signs that may erroneously suggest connective tissue disease.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adrenal Cortex Hormones / therapeutic use
  • Biopsy
  • Ceftriaxone / therapeutic use
  • Drug Therapy, Combination
  • Exanthema / etiology*
  • Glomerulonephritis, Membranous / etiology*
  • Glomerulonephritis, Membranous / pathology
  • Humans
  • Kidney / pathology
  • Male
  • Middle Aged
  • Nephrotic Syndrome / etiology*
  • Syphilis / complications
  • Syphilis / diagnosis*
  • Syphilis / drug therapy
  • Syphilis Serodiagnosis
  • Syphilis, Cutaneous / diagnosis
  • Syphilis, Cutaneous / drug therapy

Substances

  • Adrenal Cortex Hormones
  • Ceftriaxone