Effects of irbesartan on the expression of matrix metalloproteinase-2/tissue inhibitor of metalloproteinase-2 in streptozotocin-induced diabetic rat kidney

Chin Med J (Engl). 2005 Jun 20;118(12):1040-4.

Authors

Bi-cheng Liu¹, Yan Xu, Kun-ling Ma, Hai-quan Huang, Lian-fang Yin, Dian-ge Liu

Affiliation

¹ Institute of Nephrology, Zhongda Hospital, Southeast University School of Medicine, Nanjing 210009, China. kidney@jlonline.com

PMID: 15978215

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Angiotensin II Type 1 Receptor Blockers / pharmacology*
Animals
Biphenyl Compounds / pharmacology*
Creatinine / metabolism
Diabetes Mellitus, Experimental / metabolism*
Diabetes Mellitus, Experimental / pathology
Hypertrophy
Immunohistochemistry
Irbesartan
Kidney / metabolism*
Kidney / pathology
Male
Matrix Metalloproteinase 2 / analysis*
Matrix Metalloproteinase 2 / genetics
Rats
Rats, Sprague-Dawley
Streptozocin
Tetrazoles / pharmacology*
Tissue Inhibitor of Metalloproteinase-2 / analysis*
Tissue Inhibitor of Metalloproteinase-2 / genetics

Substances

Angiotensin II Type 1 Receptor Blockers
Biphenyl Compounds
Tetrazoles
Tissue Inhibitor of Metalloproteinase-2
Streptozocin
Creatinine
Matrix Metalloproteinase 2
Irbesartan