Movement disorders as sequelae of central pontine myelinolysis: report of three cases

Mov Disord. 1992;7(2):142-8. doi: 10.1002/mds.870070208.

Abstract

In three survivors of central pontine myelinolysis, dystonia (in two patients) and rest tremor (in one) were sequelae. The onset of these movements occurred 3 weeks to 5 months after the initial presentation with central pontine myelinolysis. Magnetic resonance imaging revealed basal ganglia lesions suggestive of extra-pontine myelinolysis in all three patients. We propose that the movement disorders seen in our cases are clinical correlates of extra-pontine myelinolysis.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Demyelinating Diseases / chemically induced*
  • Demyelinating Diseases / diagnosis
  • Emergencies*
  • Female
  • Follow-Up Studies
  • Humans
  • Hyponatremia / diagnosis
  • Hyponatremia / drug therapy*
  • Magnetic Resonance Imaging*
  • Middle Aged
  • Neurologic Examination / drug effects
  • Pons / drug effects*
  • Pons / pathology
  • Putamen / drug effects
  • Putamen / pathology
  • Quadriplegia / chemically induced*
  • Quadriplegia / diagnosis
  • Saline Solution, Hypertonic / administration & dosage
  • Saline Solution, Hypertonic / adverse effects*

Substances

  • Saline Solution, Hypertonic