Annexin A2: better left alone

Blood. 2005 Mar 1;105(5):1845-6. doi: 10.1182/blood-2004-12-4786.

Abstract

Zhang and McCrae demonstrate that APLA/b2GPI-mediated endothelial cell activation occurs via dimerization of annexin A2 molecules on the cell surface.

Publication types

  • Comment
  • Review

MeSH terms

  • Animals
  • Annexin A2 / metabolism
  • Annexin A2 / physiology*
  • Antibodies / pharmacology
  • Antibodies, Antiphospholipid / immunology
  • Dimerization
  • Endothelium, Vascular / pathology*
  • Glycoproteins / immunology
  • Humans
  • Thrombophilia / etiology
  • beta 2-Glycoprotein I

Substances

  • Annexin A2
  • Antibodies
  • Antibodies, Antiphospholipid
  • Glycoproteins
  • beta 2-Glycoprotein I