Aspirin use during early pregnancy and the risk of congenital abnormalities: a population-based case-control study

Bente Nørgård; Erzsébet Puhó; Andrew E Czeizel; Mette V Skriver; Henrik T Sørensen

doi:10.1016/j.ajog.2004.10.598

Aspirin use during early pregnancy and the risk of congenital abnormalities: a population-based case-control study

Am J Obstet Gynecol. 2005 Mar;192(3):922-3. doi: 10.1016/j.ajog.2004.10.598.

Authors

Bente Nørgård¹, Erzsébet Puhó, Andrew E Czeizel, Mette V Skriver, Henrik T Sørensen

Affiliation

¹ Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark.

PMID: 15746692
DOI: 10.1016/j.ajog.2004.10.598

Abstract

It is still controversial whether aspirin use during pregnancy increases the risk of certain congenital abnormalities (in particular, neural tube defects, gastroschisis, and cleft lip +/- palate). We examined the risk of selected congenital abnormalities in a large case-control dataset from Hungary and found no increased risk of such congenital abnormalities.

MeSH terms

Abnormalities, Drug-Induced / etiology*
Aspirin / adverse effects*
Case-Control Studies
Cleft Lip / chemically induced
Cleft Palate / chemically induced
Female
Fetus / drug effects
Gastroschisis / chemically induced
Humans
Neural Tube Defects / chemically induced
Pregnancy

Substances

Aspirin