High prevalence of respiratory viral infections in patients hospitalized in an intensive care unit for acute respiratory infections as detected by nucleic acid-based assays

J Clin Microbiol. 2005 Jan;43(1):455-7. doi: 10.1128/JCM.43.1.455-457.2005.

Abstract

Forty-seven bronchoalveolar lavages (BAL) were obtained from 41 patients with acute pneumonia attending an intensive care unit. By molecular diagnosis, 30% of total BAL and 63% of bacteria-negative BAL were positive for respiratory viruses. Molecular detection allows for high-rate detection of respiratory viral infections in adult patients suffering from severe pneumonia.

MeSH terms

  • Acute Disease
  • Bronchoalveolar Lavage Fluid / virology*
  • DNA, Viral / analysis
  • DNA, Viral / isolation & purification
  • Female
  • Hospitalization
  • Humans
  • Intensive Care Units*
  • Male
  • Middle Aged
  • Polymerase Chain Reaction / methods*
  • Prevalence
  • RNA, Viral / analysis
  • RNA, Viral / isolation & purification
  • Respiratory Tract Infections / epidemiology*
  • Respiratory Tract Infections / virology
  • Reverse Transcriptase Polymerase Chain Reaction / methods
  • Virus Diseases / epidemiology*
  • Virus Diseases / virology
  • Viruses / genetics
  • Viruses / isolation & purification*

Substances

  • DNA, Viral
  • RNA, Viral