IgA nephropathy in renal allografts-recurrence and graft dysfunction

Yonsei Med J. 2004 Dec 31;45(6):1043-8. doi: 10.3349/ymj.2004.45.6.1043.

Abstract

With time after transplantation, the recurrence of IgA nephropathy (IgAN) becomes a relevant cause of graft dysfunction and failure. However, only limited information has been published regarding the related clinical and histological features. In this article, we review studies on recurrent IgAN in the English literature and describe our own clinical experience. The clinical and histological features related to recurrence are still indeterminate, but features associated with graft dysfunction include proteinuria, glomerulosclerosis, mesangial proliferation, glomerular crescents and interstitial fibrosis.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Glomerulonephritis, IGA / physiopathology*
  • Glomerulonephritis, IGA / surgery*
  • Humans
  • Kidney / physiopathology*
  • Kidney Transplantation*
  • Recurrence
  • Transplantation, Homologous