Topology preservation and regularity in estimated deformation fields

Inf Process Med Imaging. 2003 Jul:18:426-37.

Abstract

A general formalism to impose topology preserving regularity on a given irregular deformation field is presented. The topology preservation conditions are derived with regard to the discrete approximations to the deformation field Jacobian in a two-dimensional image registration problem. The problem of enforcing topology preservation onto a given deformation field is formulated in terms of the deformation gradients, and solved using a cyclic projections approach. The generalization of the developed algorithm leads to a deformation field regularity control by limiting the per voxel volumetric change within a prescribed interval. Extension of the topology preservation conditions onto a three-dimensional registration problem is also presented, together with a comparative analysis of the proposed algorithm with respect to a Gaussian regularizer that enforces the same topology preservation conditions.

Publication types

  • Comparative Study
  • Evaluation Study
  • Validation Study

MeSH terms

  • Algorithms*
  • Brain / anatomy & histology*
  • Computer Simulation
  • Elasticity
  • Humans
  • Image Enhancement / methods
  • Image Interpretation, Computer-Assisted / methods*
  • Imaging, Three-Dimensional / methods*
  • Models, Biological
  • Models, Statistical
  • Pattern Recognition, Automated*
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Subtraction Technique*