Neonatal lower motor neuron syndrome associated with maternal neuropathy with anti-GM1 IgG

Neurology. 2004 Jul 27;63(2):379-81. doi: 10.1212/01.wnl.0000130193.32776.da.

Abstract

The authors report a newborn with motor neuropathy associated with anti-GM1 antibodies from an affected mother. This finding suggests that the disorder was due to transplacental transfer of pathogenic antibodies.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antibody Specificity
  • Female
  • G(M1) Ganglioside / immunology*
  • Humans
  • Immunity, Maternally-Acquired*
  • Immunoglobulin G / immunology*
  • Infant, Newborn
  • Isoantibodies / immunology*
  • Maternal-Fetal Exchange
  • Motor Neuron Disease / congenital*
  • Motor Neuron Disease / immunology
  • Neural Conduction
  • Paraproteinemias / immunology
  • Pregnancy
  • Pregnancy Complications / immunology*

Substances

  • Immunoglobulin G
  • Isoantibodies
  • G(M1) Ganglioside