Abstract
The authors report a newborn with motor neuropathy associated with anti-GM1 antibodies from an affected mother. This finding suggests that the disorder was due to transplacental transfer of pathogenic antibodies.
MeSH terms
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Adult
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Antibody Specificity
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Female
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G(M1) Ganglioside / immunology*
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Humans
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Immunity, Maternally-Acquired*
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Immunoglobulin G / immunology*
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Infant, Newborn
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Isoantibodies / immunology*
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Maternal-Fetal Exchange
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Motor Neuron Disease / congenital*
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Motor Neuron Disease / immunology
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Neural Conduction
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Paraproteinemias / immunology
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Pregnancy
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Pregnancy Complications / immunology*
Substances
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Immunoglobulin G
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Isoantibodies
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G(M1) Ganglioside