[Legionella pneumophila pneumonia community epidemic outbreak in Barcelona: "The Barceloneta outbreak". Effect on the early diagnosis and treatment]

Rev Clin Esp. 2004 Feb;204(2):70-4. doi: 10.1157/13058800.
[Article in Spanish]

Abstract

Objective: Clinical and microbiological descriptive analysis of the outbreak of community legionnaire's disease recorded in the Barcelona's Barcelonesa neighborhood in November 2000.

Patients and methods: Retrospective review of the epidemiological and clinical manifestations, as well as the evolution of the cases of Legionella pneumophila pneumonia associated with the outbreak and cared of in the Hospital del Mar.

Results: The 48 patients evaluated, all of them with confirmed diagnoses, represent 89% of the cases communicated. Seventy-five percent of patients showed some underlying disease, 54% had some criterion for severity, and mortality was 4%. In 81% of cases the detection of the antigen of Legionella pneumophila in urine was the diagnostic method.

Conclusions: The detection in urine of the Legionella pneumophila antigen makes possible the early diagnosis of legionnaire's disease, particularly in epidemic outbreaks, which that facilitates the fast establishment of the adequate treatment and contributes to the reduction in mortality even in patients of high risk.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Anti-Bacterial Agents / therapeutic use
  • Antigens, Bacterial / analysis
  • Community-Acquired Infections / diagnosis
  • Community-Acquired Infections / drug therapy
  • Community-Acquired Infections / epidemiology*
  • Disease Outbreaks*
  • Female
  • Humans
  • Legionella pneumophila / immunology
  • Legionella pneumophila / isolation & purification*
  • Legionnaires' Disease / diagnosis
  • Legionnaires' Disease / drug therapy
  • Legionnaires' Disease / epidemiology*
  • Male
  • Middle Aged
  • Retrospective Studies
  • Risk Factors
  • Seroepidemiologic Studies
  • Spain / epidemiology

Substances

  • Anti-Bacterial Agents
  • Antigens, Bacterial