Effectiveness of cardiac surgery in trisomies 13 and 18 (from the Pediatric Cardiac Care Consortium)

Am J Cardiol. 2004 Mar 15;93(6):801-3. doi: 10.1016/j.amjcard.2003.12.012.

Abstract

Because of severely reduced lifespan in children with trisomies 13 and 18, surgical repair of congenital heart lesions has rarely been offered. With data from a multicenter registry, we report 35 cases of cardiac surgery in infants and children with trisomy 13 or 18 with a 91% hospital survival rate. Those patients without an extended preoperative ventilatory requirement did not require prolonged mechanical ventilation after surgery.

MeSH terms

  • Canada / epidemiology
  • Cardiac Surgical Procedures / statistics & numerical data
  • Child
  • Child, Preschool
  • Chromosomes, Human, Pair 13*
  • Chromosomes, Human, Pair 18*
  • Europe / epidemiology
  • Female
  • Heart Defects, Congenital / mortality*
  • Heart Defects, Congenital / surgery*
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Postoperative Complications
  • Registries
  • Respiration, Artificial
  • Retrospective Studies
  • Survival Analysis
  • Trisomy*
  • United States / epidemiology