Active or prior GB virus C infection does not protect against vertical transmission of HIV in coinfected women from Tanzania

Clin Infect Dis. 2004 Mar 15;38(6):e46-8. doi: 10.1086/382079. Epub 2004 Mar 1.

Abstract

To determine whether GB virus C (GBV-C) infection is associated with protection against vertical transmission of human immunodeficiency virus (HIV), we tested 186 HIV-positive pregnant women for GBV-C. Neither active nor prior GBV-C infection was associated with a lower rate of HIV acquisition among infants. Thus, GBV-C does not appear to protect against perinatal HIV acquisition.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Female
  • Flaviviridae Infections / complications*
  • GB virus C*
  • HIV Infections / complications
  • HIV Infections / transmission*
  • Humans
  • Infectious Disease Transmission, Vertical*
  • Pregnancy
  • Pregnancy Complications, Infectious / virology*
  • Tanzania