Abstract
Helicobacter pylori are bacteria that have coevolved with humans to be transmitted from person to person and to persistently colonize the stomach. Their population structure is a model for the ecology of the indigenous microbiota. A well-choreographed equilibrium between bacterial effectors and host responses permits microbial persistence and health of the host but confers risk of serious diseases, including peptic ulceration and gastric neoplasia.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Ghrelin
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Helicobacter Infections / immunology
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Helicobacter Infections / metabolism
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Helicobacter Infections / physiopathology*
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Helicobacter pylori / immunology
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Helicobacter pylori / metabolism
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Helicobacter pylori / pathogenicity*
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Humans
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Inflammation / immunology
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Inflammation / metabolism
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Inflammation / microbiology
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Leptin / metabolism
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Peptide Hormones / metabolism
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Stomach / microbiology*
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Stomach Diseases / microbiology*
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Stomach Diseases / physiopathology
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Virulence
Substances
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Ghrelin
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Leptin
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Peptide Hormones