Improving the bacteriological diagnosis of tuberculous meningitis

J Clin Microbiol. 2004 Jan;42(1):378-9. doi: 10.1128/JCM.42.1.378-379.2004.

Abstract

We made a bacteriological diagnosis of tuberculous meningitis in 107 of 132 (81%) adults with clinical tuberculous meningitis: acid-fast bacilli were seen in 77 of 132 (58%) and cultured from 94 of 132 (71%). Volume of cerebrospinal fluid, duration of symptoms, cerebrospinal fluid neutrophils, lactate, and glucose were all independently associated with bacteriological confirmation.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Cerebrospinal Fluid / microbiology
  • Humans
  • Mycobacterium tuberculosis / isolation & purification*
  • Prospective Studies
  • Tuberculosis, Meningeal / cerebrospinal fluid
  • Tuberculosis, Meningeal / microbiology*