Littoral cell angioma of the spleen in a patient with severe aplastic anaemia

Haematologica. 2003 Nov;88(11):ECR33.

Abstract

Littoral cell angioma (LCA) is a rare benign tumour of the spleen. We describe a patient with aplastic anaemia who, following multiple treatments with rabbit and horse Anti-Thymocyte Globulin and anabolic steroids developed marked splenomegaly and hypersplenism. LCA was diagnosed post splenectomy. This is the first case of LCA associated with aplastic anaemia and its treatment.

Publication types

  • Case Reports

MeSH terms

  • Anemia, Aplastic / complications*
  • Anemia, Aplastic / drug therapy
  • Animals
  • Antilymphocyte Serum / adverse effects
  • Blood Transfusion
  • Cyclosporine / adverse effects
  • Cyclosporine / therapeutic use
  • Female
  • Hemangioma / chemically induced
  • Hemangioma / complications*
  • Horses
  • Humans
  • Hypersplenism / etiology
  • Immunosuppressive Agents / adverse effects
  • Immunosuppressive Agents / therapeutic use
  • Middle Aged
  • Oxymetholone / adverse effects
  • Oxymetholone / therapeutic use
  • Rabbits
  • Splenectomy
  • Splenic Neoplasms / chemically induced
  • Splenic Neoplasms / complications*
  • T-Lymphocytes

Substances

  • Antilymphocyte Serum
  • Immunosuppressive Agents
  • Cyclosporine
  • Oxymetholone