Rapid onset childhood cataracts leading to the diagnosis of autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy

Am J Ophthalmol. 2003 Nov;136(5):951-2. doi: 10.1016/s0002-9394(03)00479-3.

Abstract

Purpose: To report a case of bilateral cataracts in a child that led to diagnosis of autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy.

Design: Observational case report.

Methods: A 12-year-old boy was being investigated for weakness, lethargy, short stature, and blurred vision. He developed bilateral, dense cataracts over a 2-week period. He was found to be hypocalcemic and diagnosed with hypoparathyroidism and autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy.

Results: Because of hypoparathyroidism, adrenocortical failure, and insulin-dependent diabetes, it was 9 months before the patient's metabolic imbalance was brought under sufficient control to allow cataract surgery.

Conclusions: Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy should be considered with diagnoses of hypocalcemic cataract.

Publication types

  • Case Reports

MeSH terms

  • Calcium / blood
  • Cataract / diagnosis*
  • Cataract / therapy
  • Child
  • Humans
  • Hypocalcemia / diagnosis*
  • Hypoparathyroidism / diagnosis*
  • Lens Implantation, Intraocular
  • Male
  • Parathyroid Hormone / blood
  • Phacoemulsification
  • Polyendocrinopathies, Autoimmune / diagnosis*
  • Visual Acuity

Substances

  • Parathyroid Hormone
  • Calcium