Abstract
The bacteriological and clinical efficacy and side effects of cefoperazone were studied in 45 patients with severe and moderate purulent inflammatory diseases. The study showed that its bacteriological and clinical efficacy was high in cases with peritonitis, cholecystitis, respiratory and urinary infections, as well as those of the eye and soft tissues. The general clinical efficacy amounted to 95.6 per cent. The number of the side effects was insignificant. This made it possible to recommend the use of cefoperazone in the therapy of many purulent inflammatory diseases, as well as in empirical therapy.
Publication types
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Comparative Study
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English Abstract
MeSH terms
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Adult
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Age Factors
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Bacteria, Anaerobic / drug effects*
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Bacterial Infections / drug therapy*
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Bacterial Infections / microbiology
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Cefoperazone / administration & dosage
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Cefoperazone / pharmacology
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Cefoperazone / therapeutic use*
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Child
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Cholecystitis / drug therapy*
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Cholecystitis / microbiology
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Enterobacteriaceae Infections / drug therapy
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Enterobacteriaceae Infections / microbiology
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Humans
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In Vitro Techniques
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Peritonitis / drug therapy*
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Peritonitis / microbiology
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Pseudomonas Infections / drug therapy
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Pseudomonas Infections / microbiology
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Respiratory Tract Infections / drug therapy*
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Respiratory Tract Infections / microbiology
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Staphylococcal Infections / drug therapy
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Staphylococcal Infections / microbiology
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Streptococcal Infections / drug therapy
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Streptococcal Infections / microbiology
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Urinary Tract Infections / drug therapy*
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Urinary Tract Infections / microbiology