Acute axonal idiopathic polyneuropathy: a Guillain-Barré syndrome variant?

Ital J Neurol Sci. 1992 Sep;13(6):481-6. doi: 10.1007/BF02230868.

Abstract

We report 7 cases of acute polyneuropathy fitting the NINDS diagnostic criteria for GBS. Electrophysiological study and sural nerve biopsy revealed a picture of axonal polyneuropathy, without changes suggesting demyelination. We discuss whether the acute idiopathic axonal neuropathy belongs to the GBS spectrum or represents a separate clinico-pathological entity.

MeSH terms

  • Adult
  • Aged
  • Axons* / physiology
  • Biopsy
  • Cerebrospinal Fluid / cytology
  • Cerebrospinal Fluid Proteins / analysis
  • Electrophysiology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Nervous System Diseases / diagnosis*
  • Nervous System Diseases / pathology
  • Nervous System Diseases / physiopathology
  • Polyradiculoneuropathy / diagnosis*
  • Polyradiculoneuropathy / pathology
  • Polyradiculoneuropathy / physiopathology
  • Sural Nerve / pathology

Substances

  • Cerebrospinal Fluid Proteins