Evidence of Toscana virus circulation in Umbria: first report

Eur J Epidemiol. 2003;18(5):457-9. doi: 10.1023/a:1024295710118.

Abstract

To evaluate, for the first time, circulation and clinical expression of Toscana virus (ToSv) in Umbria region we studied: (1) 93 cases of aseptic meningitis and meningoencephalitis admitted to our Department from 1989 to 2001 with negative results for common neurotropic virus; (2) 50 healthy subjects. Specific antibodies (IgM and IgG) anti-TOSv were found in 36.6% of aseptic meningitis, in 6.06% of meningoencephalitis and (IgG) in 16% of healthy subjects.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Cohort Studies
  • Enzyme-Linked Immunosorbent Assay
  • Female
  • Humans
  • Immunoglobulin G / blood
  • Immunoglobulin G / immunology
  • Immunoglobulin M / blood
  • Immunoglobulin M / immunology
  • Italy / epidemiology
  • Male
  • Meningitis / blood*
  • Meningitis / epidemiology
  • Meningitis / virology
  • Meningoencephalitis / blood
  • Meningoencephalitis / epidemiology
  • Meningoencephalitis / virology
  • Middle Aged
  • Sandfly fever Naples virus / immunology
  • Sandfly fever Naples virus / isolation & purification
  • Sandfly fever Naples virus / pathogenicity*
  • Seroepidemiologic Studies

Substances

  • Immunoglobulin G
  • Immunoglobulin M