Molecular-size reduction of a potent CXCR4-chemokine antagonist using orthogonal combination of conformation- and sequence-based libraries

Angew Chem Int Ed Engl. 2003 Jul 21;42(28):3251-3. doi: 10.1002/anie.200351024.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Oligopeptides / chemistry*
  • Peptide Library
  • Peptides, Cyclic / chemistry*
  • Peptides, Cyclic / pharmacology
  • Protein Conformation
  • Receptors, CXCR4 / antagonists & inhibitors*

Substances

  • Oligopeptides
  • Peptide Library
  • Peptides, Cyclic
  • Receptors, CXCR4
  • T140 peptide