Is the Achilles' heel for prostate cancer therapy a gain of function in androgen receptor signaling?

J Clin Endocrinol Metab. 2003 Jul;88(7):2972-82. doi: 10.1210/jc.2002-022038.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Cell Differentiation / physiology
  • Drug Design
  • Humans
  • Male
  • Prostatic Neoplasms / drug therapy*
  • Prostatic Neoplasms / pathology
  • Prostatic Neoplasms / physiopathology*
  • Receptors, Androgen / genetics
  • Receptors, Androgen / metabolism*
  • Signal Transduction / physiology*

Substances

  • Receptors, Androgen