Hypertrophic pachymeningitis: case report

Arq Neuropsiquiatr. 2003 Mar;61(1):107-11. doi: 10.1590/s0004-282x2003000100021. Epub 2003 Apr 16.

Abstract

Hypertrophic pachymeningits is an unusual cause of neurological symptoms and is often secondary to infections, carcinomatosis or inflammatory diseases. It may also be idiopathic. We report a case of pachymeningitis which was manifested primarily by psychosis and visual loss with optic atrophy and destruction of nasal septum. The patient, a 45 year old woman was submitted to extensive investigation without evidence of any underlying disease. A meningeal biopsy was performed and showed a mostly unspecific inflammatory process with extensive fibrosis of the dura and few early stage granulomas. These findings suggest either neurosarcoidosis or idiopathic hypertrophic pachymeningitis.

Publication types

  • Case Reports

MeSH terms

  • Biopsy
  • Dura Mater / pathology
  • Female
  • Gadolinium
  • Humans
  • Hypertrophy
  • Magnetic Resonance Angiography
  • Meningitis / etiology*
  • Meningitis / pathology
  • Middle Aged
  • Nasal Septum / pathology
  • Optic Nerve Diseases / complications

Substances

  • Gadolinium