Abstract
One new phenolic glycoside named benzoylsalireposide (1) along with one known phenolic glycoside named salireposide (2) have been isolated from Symplocos racemosa. Four other known compounds i.e. beta-amyrin (3), oleonolic acid (4), beta-sitosterol (5) and beta-sitosterol glycoside (6) were also isolated from this plant. The structure elucidation of the isolated compounds was based primarily on 1D- and 2D-NMR analysis, including COSY, HMQC, and HMBC correlations. The compound 1 and 2 showed inhibitory activity against snake venom phosphodiesterase I.
MeSH terms
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Animals
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Glycosides / chemistry
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Glycosides / isolation & purification
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Glycosides / pharmacology*
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Magnetic Resonance Spectroscopy
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Magnoliopsida / chemistry*
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Phenols / chemistry
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Phenols / isolation & purification
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Phenols / pharmacology*
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Phosphodiesterase I
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Phosphodiesterase Inhibitors / chemistry
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Phosphodiesterase Inhibitors / isolation & purification
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Phosphodiesterase Inhibitors / pharmacology*
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Phosphoric Diester Hydrolases / metabolism*
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Plants, Medicinal / chemistry
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Snake Venoms / enzymology
Substances
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Glycosides
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Phenols
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Phosphodiesterase Inhibitors
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Snake Venoms
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Phosphoric Diester Hydrolases
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Phosphodiesterase I
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phosphodiesterase I, snake venom