The goal of this synthesis is to provide a comprehensive assessment of the literature associated with dating violence in adolescence. Previous research findings on the prevalence, risk factors associated with victimization and perpetration, and potential health outcomes of dating violence are discussed. The importance of designing developmentally and culturally competent dating violence prevention and intervention strategies in the clinical setting is emphasized. This review is intended to assist health care professionals to develop interventions in their clinical settings to prevent and reduce adolescent dating violence.