Melanoma metastatic to central neurocytoma: a novel case of tumor-to-tumor metastasis

J Neurooncol. 2003 Feb;61(3):209-14. doi: 10.1023/a:1022599622949.

Abstract

We report a case of a 43-year-old man with known metastatic melanoma and two intracranial tumors, one of which was resected and confirmed to be melanoma. At autopsy, the second lesion was found to be a central neurocytoma harboring metastatic melanoma. To our knowledge, this represents the first reported case of tumor-to-tumor metastasis to a central neurocytoma. The most common pattern of tumor-to-tumor metastasis for intracranial neoplasms, in which an aggressive high-grade malignancy serves as the source tumor and a more indolent neoplasm serves as the recipient tumor, is affirmed by the present novel example.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cell Transformation, Neoplastic / pathology
  • Cerebellar Neoplasms / diagnosis
  • Cerebellar Neoplasms / secondary*
  • Cerebral Ventricle Neoplasms / diagnosis
  • Cerebral Ventricle Neoplasms / secondary*
  • Humans
  • Lung Neoplasms / diagnosis
  • Lung Neoplasms / secondary
  • Lymphatic Metastasis
  • Male
  • Melanoma / diagnosis*
  • Melanoma / secondary*
  • Neoplasm Invasiveness
  • Neoplasms, Multiple Primary / diagnosis*
  • Neoplasms, Unknown Primary / diagnosis
  • Neurocytoma / diagnosis*
  • Septum Pellucidum / pathology