Effect of atorvastatin (80 mg) and simvastatin (40 mg) on plasma fibrinogen levels and on carotid intima media thickness in patients with familial hypercholesterolemia

Am J Cardiol. 2003 Mar 1;91(5):604-6. doi: 10.1016/s0002-9149(02)03318-0.
No abstract available

Publication types

  • Clinical Trial
  • Comparative Study
  • Multicenter Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Administration, Oral
  • Adult
  • Atorvastatin
  • Biomarkers / blood
  • Carotid Arteries / drug effects
  • Carotid Arteries / pathology
  • Dose-Response Relationship, Drug
  • Double-Blind Method
  • Drug Administration Schedule
  • Female
  • Fibrinogen / analysis*
  • Fibrinogen / drug effects
  • Follow-Up Studies
  • Heptanoic Acids / administration & dosage*
  • Humans
  • Hyperlipoproteinemia Type II / diagnosis
  • Hyperlipoproteinemia Type II / drug therapy*
  • Male
  • Middle Aged
  • Probability
  • Pyrroles / administration & dosage*
  • Reference Values
  • Severity of Illness Index
  • Simvastatin / administration & dosage*
  • Treatment Outcome
  • Tunica Media / drug effects*
  • Tunica Media / pathology*

Substances

  • Biomarkers
  • Heptanoic Acids
  • Pyrroles
  • Fibrinogen
  • Atorvastatin
  • Simvastatin