Relapsing cutaneous alternariosis in a kidney transplant recipient cured with liposomal amphotericin B

E Merino; J Bañuls; V Boix; A Franco; J Guijarro; J Portilla; I Betlloch

doi:10.1007/s10096-002-0856-4

Relapsing cutaneous alternariosis in a kidney transplant recipient cured with liposomal amphotericin B

Eur J Clin Microbiol Infect Dis. 2003 Jan;22(1):51-3. doi: 10.1007/s10096-002-0856-4. Epub 2003 Jan 16.

Authors

E Merino¹, J Bañuls, V Boix, A Franco, J Guijarro, J Portilla, I Betlloch

Affiliation

¹ Unit of Infectious Diseases, Hospital General Universitario de Alicante, Pintor Baeza s/n, 03012 Alicante, Spain. merino_luc@gva.es

PMID: 12582745
DOI: 10.1007/s10096-002-0856-4

Abstract

An immunosuppressed patient who presented with unusual clinical signs of cutaneous alternariosis, including papular, nodular and verrucous lesions of the forearms, is reported. In spite of continuous treatment with oral itraconazole for 6 months, a large, progressive, necrotic ulcer appeared on the patient's left leg. Liposomal amphotericin B was then administered (total dose, 750 mg) with excellent clinical results.

Publication types

Case Reports

MeSH terms

Alternaria / drug effects*
Alternaria / isolation & purification*
Amphotericin B / administration & dosage*
Antifungal Agents / administration & dosage*
Biopsy, Needle
Dermatomycoses / diagnosis
Dermatomycoses / drug therapy*
Dermatomycoses / immunology
Follow-Up Studies
Humans
Immunocompromised Host
Immunohistochemistry
Kidney Transplantation / immunology*
Leg Ulcer / drug therapy*
Leg Ulcer / microbiology
Liposomes
Male
Middle Aged
Opportunistic Infections / diagnosis
Opportunistic Infections / drug therapy*
Opportunistic Infections / immunology
Recurrence
Risk Assessment
Severity of Illness Index
Treatment Outcome

Substances

Antifungal Agents
Liposomes
Amphotericin B