[Epstein-Barr virus and Hodgkin's lymphoma]

Ugeskr Laeger. 2002 Dec 9;164(50):5924-7.
[Article in Danish]

Abstract

The suspicion that Hodgkin's lymphoma, previously known as Hodgkin's disease, may have an infectious etiology has existed for many years. The assumption rests on epidemiological characteristics, in particular a strong correlation between socio-economic status and risk of Hodgkin's lymphoma in young adults, as well as both serological and molecular biological evidence that the Epstein-Barr virus is involved in the development of up to 50% of all cases of Hodgkin's lymphoma. We present the current epidemiological, serological and molecular biological evidence for an infectious etiology to Hodgkin's lymphoma with emphasis on the association with Epstein-Barr virus.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Adult
  • Causality
  • Child
  • Comorbidity
  • Epstein-Barr Virus Infections / epidemiology
  • Epstein-Barr Virus Infections / virology*
  • Female
  • Hodgkin Disease / epidemiology
  • Hodgkin Disease / virology*
  • Humans
  • Incidence
  • Male
  • Risk Factors
  • Scandinavian and Nordic Countries / epidemiology
  • Socioeconomic Factors