Abstract
We describe a patient with acute isolated bulbar palsy following enteritis. A 29-year-old man developed dysphagia and nasal voice without limb weakness, ataxia, or areflexia. High titres of serum anti-GT1a and anti-Campylobacter jejuni IgG antibodies were detected. He was treated with plasmapheresis, resulting in rapid clinical improvement. This case suggests that an acute isolated bulbar palsy may be caused by a pathology relating to Guillain-Barré syndrome (GBS), in which anti-GT1a IgG antibody may have a role.
MeSH terms
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Adult
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Autoantibodies / analysis
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Bulbar Palsy, Progressive / blood
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Bulbar Palsy, Progressive / complications
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Bulbar Palsy, Progressive / immunology*
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Campylobacter Infections / complications
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Campylobacter Infections / immunology*
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Campylobacter jejuni / immunology*
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Enteritis / complications
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Enteritis / immunology*
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Gangliosides / immunology*
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Guillain-Barre Syndrome / complications
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Humans
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Immunoglobulin G / analysis
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Immunoglobulin G / immunology*
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Male
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Plasmapheresis
Substances
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Autoantibodies
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Gangliosides
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Immunoglobulin G
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trisialoganglioside GT1