A comparison of catecholamine and cortisol responses of young lambs and calves to painful husbandry procedures

Aust Vet J. 2002 Apr;80(4):228-33. doi: 10.1111/j.1751-0813.2002.tb10820.x.

Abstract

Aim: To compare the changes in plasma concentrations of noradrenaline, adrenaline and cortisol in lambs after ring castration plus tailing and in calves after dehorning with or without prior local anaesthesia.

Methods: Male lambs were castrated and tailed with rings and calves were dehorned by amputation using a scoop with or without prior local anaesthesia. Blood samples were taken before and after treatment and plasma concentrations of noradrenaline, adrenaline and cortisol were determined.

Results: Castration plus tailing of lambs resulted in a rapid increase in noradrenaline concentrations, a lack of an adrenaline response and a marked increase in cortisol concentration. There were similar changes in catecholamine concentrations in calves that were dehorned both with and without local anaesthetic, with adrenaline being elevated within 5 min of treatment and noradrenaline exhibiting a more protracted response. Dehorning caused a marked cortisol increase which was reduced to control concentrations by local anaesthesia for as long as the associated nerve blockade lasted.

Conclusions: The very short-lived adrenaline responses in calves were attributed to dehorning-induced nociceptor input leading to sympathetic stimulation of the adrenal medulla. The longer lasting noradrenaline responses in lambs and calves were thought be due to 'wash-out' of noradrenaline from damaged tissue associated with rings and amputation wounds, respectively.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Animals, Newborn
  • Catecholamines / blood*
  • Cattle / physiology*
  • Cattle / surgery
  • Epinephrine / blood
  • Horns / surgery
  • Hydrocortisone / blood*
  • Male
  • Norepinephrine / blood
  • Orchiectomy / veterinary
  • Pain / prevention & control
  • Pain / veterinary*
  • Pain Measurement / veterinary
  • Sheep / physiology*
  • Sheep / surgery
  • Tail / surgery
  • Time Factors

Substances

  • Catecholamines
  • Hydrocortisone
  • Norepinephrine
  • Epinephrine