Integrating functions at the kinetochore

Soni L Shimoda; Frank Solomon

doi:10.1016/s0092-8674(02)00712-2

Integrating functions at the kinetochore

Cell. 2002 Apr 5;109(1):9-12. doi: 10.1016/s0092-8674(02)00712-2.

Authors

Soni L Shimoda¹, Frank Solomon

Affiliation

¹ Department of Biology and Center for Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

PMID: 11955441
DOI: 10.1016/s0092-8674(02)00712-2

Abstract

Kinetochore components have catalytic as well as structural activities. New evidence illustrates how these proteins integrate spindle morphogenesis with regulation of the timing and accuracy of chromosome segregation.

Publication types

Review

MeSH terms

Anaphase / physiology
Animals
Chromosome Segregation / physiology
Humans
Kinetochores / physiology*
Macromolecular Substances
Microtubules / physiology
Mitosis / physiology*
Spindle Apparatus / physiology*

Substances

Macromolecular Substances