A method of molecular-genetic diagnosis of diseases in hereditary predisposition developed by the authors is novel in geriatric practice. It allows to predict such prevalent age-specific diseases as ischemic heart disease, hypertension, noninsulin-dependent diabetes mellitus, Alzheimer's and some malignancies. Assessment of molecular-genetic, clinical and laboratory data can identify predisposition or early symptoms of the disease. Special system of prophylaxis and pathogenetic treatment is designed to prevent development of genetically predetermined age-specific diseases.