Benign thymic hyperplasia after chemotherapy for acute myeloid leukemia

Eur J Haematol. 2001 Oct;67(4):252-4. doi: 10.1034/j.1600-0609.2001.00536.x.

Abstract

Thymic hyperplasia can occur after cytotoxic therapy for various malignancies. The possible cause could be rebound enlargement after initial atrophy caused by these drugs. During the treatment of hematological malignancies this could be a cause of great concern. We report here a case of thymic hyperplasia after chemotherapy for acute myeloid leukemia. Awareness of this unusual side-effect may prevent needless investigation and therapy.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Child
  • Cytarabine / administration & dosage
  • Daunorubicin / administration & dosage
  • Female
  • Humans
  • Hyperplasia
  • Leukemia, Promyelocytic, Acute / drug therapy*
  • Leukemia, Promyelocytic, Acute / pathology
  • Pseudotumor Cerebri / chemically induced
  • Radiography
  • Sweet Syndrome / etiology
  • Thymus Gland / diagnostic imaging
  • Thymus Gland / drug effects
  • Thymus Gland / pathology*
  • Tretinoin / adverse effects*
  • Tretinoin / therapeutic use

Substances

  • Cytarabine
  • Tretinoin
  • Daunorubicin