[The clinical features and study on therapeutic effects of fungal keratitis]

Zhonghua Yan Ke Za Zhi. 2000 Sep;36(5):358-61.
[Article in Chinese]

Abstract

Objective: To review the clinical features and therapeutic effects of fungal keratitis (FK).

Methods: 110 cases (110 eyes) with the disease were divided into two types: hyphomycetic keratitis in 94 eyes and candida keratitis in 16 eyes. The clinical features and therapeutic effects of the two types were observed and compared.

Results: The hyphomycetic keratitis generally had a plant traumatic history. The border of corneal infiltration was not clear with feather edges, and had a tendency to penetrate into the deep stroma of cornea. There were endothelial plaques, hypopyon and bad therapeutic effects. The pathogenicity of cardida keratitis (CK) was related to the local long-term use of glucocorticoid, the fungus seldom expanded into the deep corneal layers and infiltrated into the inner eye. Its therapeutic effects were better. The border of CK was characterized with limitations, and was clear.

Conclusions: The clinical features of the two types are different. The clinical features caused by different or the same pathogenic fungi show great variations. Early diagnoses, correct use of medicine and operation are the key points to increase the curative rate.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Candida / isolation & purification
  • Candidiasis / microbiology
  • Eye Infections, Fungal / drug therapy
  • Eye Infections, Fungal / pathology*
  • Female
  • Humans
  • Keratitis / microbiology*
  • Male
  • Middle Aged
  • Mitosporic Fungi / isolation & purification
  • Yeasts / isolation & purification