[Clinical observation on 51 patients of acute myocardial infarction treated with thrombolytic therapy combined with Chinese herbal medicine]

Zhongguo Zhong Xi Yi Jie He Za Zhi. 1999 Aug;19(8):461-2.
[Article in Chinese]

Abstract

Objective: To assess the efficacy of thrombolytic therapy combined with Chinese herbal medicine (CHM) in treating acute myocardial infarction (AMI).

Methods: One hundred and one cases of AMI were divided randomly into two groups. The treated group treated with thrombolytic therapy combined with CHM and the control group treated with thrombolytic therapy alone. The criteria of patency of coronary artery were conducted according to the referential standard of thrombolytic therapy in treating AMI introduced by Chinese Angiocardiopathy Medical Journal, 1991.

Results: The patency rate of coronary artery of the two groups were 68.63% and 56.00%, the four-week mortality 3.92% and 10.00%, hemorrhage occurrence 1.96% and 10.00%, congestive heart failure occurrence 5.88% and 16.00%, severe arrhythmia occurrence 11.76% and 22.00%, and the shock occurrence 3.92% and 8.00% respectively. The difference between the two groups was significant, P < 0.01, P < 0.05.

Conclusion: The effect of the treated group was better and the complication occurrence of the treated group was lower than those of the control group.

Publication types

  • Clinical Trial
  • English Abstract
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Aged
  • Drug Therapy, Combination
  • Drugs, Chinese Herbal / therapeutic use*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Myocardial Infarction / drug therapy*
  • Thrombolytic Therapy*
  • Urokinase-Type Plasminogen Activator / therapeutic use*

Substances

  • Drugs, Chinese Herbal
  • Urokinase-Type Plasminogen Activator