Immunomodulators

Pediatr Infect Dis J. 2001 Oct;20(10):995-6. doi: 10.1097/00006454-200110000-00015.

Abstract

Cytokine immunomodulators have received considerable attention. Interferon-alpha has broad clinical application for treatment of a number of viruses. The neutrophil-stimulatory effects of interferon-gamma are useful in neutrophil disorders. TNF antagonists are useful in rheumatoid arthritis but carry the risk of activating intracellular organisms. Hemopoietic growth factors have considerable clinical effect in patients receiving immunosuppressive chemotherapy. A number of cytokines and cytokine antagonists are undergoing research development.

Publication types

  • Review

MeSH terms

  • Adjuvants, Immunologic / therapeutic use*
  • Antineoplastic Agents / therapeutic use
  • Antiviral Agents / therapeutic use
  • Granulocyte Colony-Stimulating Factor / therapeutic use*
  • Humans
  • Interferons / therapeutic use*
  • Neoplasm Proteins / therapeutic use*
  • Receptors, Tumor Necrosis Factor, Type II
  • Tumor Necrosis Factor Decoy Receptors

Substances

  • Adjuvants, Immunologic
  • Antineoplastic Agents
  • Antiviral Agents
  • Neoplasm Proteins
  • Receptors, Tumor Necrosis Factor, Type II
  • Tumor Necrosis Factor Decoy Receptors
  • Granulocyte Colony-Stimulating Factor
  • Interferons