Craniopharyngioma presenting during pregnancy 4 years after a normal magnetic resonance imaging scan: case report

Neurosurgery. 2001 Oct;49(4):1014-6; conclusion 1016-7. doi: 10.1097/00006123-200110000-00045.

Abstract

Objective and importance: Craniopharyngiomas, epithelial tumors of the hypothalamic and pituitary region, are thought to have congenital origins. It has been postulated that hormonal influences may stimulate growth in adults. This report describes a case and reviews the literature.

Clinical presentation: The case is discussed of a 39-year-old woman who experienced symptoms from a craniopharyngioma diagnosed during a pregnancy that resulted from in vitro fertilization. A magnetic resonance imaging scan performed 4 years previously had disclosed nothing abnormal.

Intervention: The patient underwent a right frontotemporal craniotomy with total resection of the suprasellar tumor, which was dissected from the pituitary stalk.

Conclusion: This case suggests a possible link in the adult patient between the growth of this supposedly congenital tumor and hormonal stimulation.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Brain / pathology
  • Craniopharyngioma / diagnosis*
  • Craniopharyngioma / pathology
  • Craniopharyngioma / surgery
  • Craniotomy
  • Female
  • Follow-Up Studies
  • Humans
  • Magnetic Resonance Imaging*
  • Pituitary Neoplasms / diagnosis*
  • Pituitary Neoplasms / pathology
  • Pituitary Neoplasms / surgery
  • Pregnancy
  • Pregnancy Complications, Neoplastic / diagnosis*
  • Pregnancy Complications, Neoplastic / pathology
  • Pregnancy Complications, Neoplastic / surgery