[Significance of the activity of indicators of the fibrinolytic system on assessment of the hemostatic state]

O M Savchuk; M Sh Hamisoniia; O I Kizim; T M Platonova

[Significance of the activity of indicators of the fibrinolytic system on assessment of the hemostatic state]

Fiziol Zh (1994). 2001;47(3):58-63.

[Article in Ukrainian]

Authors

O M Savchuk¹, M Sh Hamisoniia, O I Kizim, T M Platonova

Affiliation

¹ A. V. Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kiev.

PMID: 11519252

Abstract

Complex analysis of pregnant women haemostasis system before and after caesarian section allowed find the coagulation system activation. It was shown the thrombotic markers accumulation, AT III and protein C levels decrease. Also change of ratio fibrinolytic system components was exposed. Definition of t-PA and PAI-1 activities can be used as prognostic markers of the fibrinolytic chain haemostasis system disfunction.

Publication types

English Abstract

MeSH terms

Antithrombin III / metabolism
Biomarkers / blood*
Cesarean Section*
Disseminated Intravascular Coagulation / blood
Disseminated Intravascular Coagulation / physiopathology
Female
Fibrinolysis / physiology*
Hemostasis / physiology*
Humans
Plasminogen / metabolism
Plasminogen Activator Inhibitor 1 / metabolism
Postoperative Care
Pregnancy
Preoperative Care
Prognosis
Protein C / metabolism
Tissue Plasminogen Activator / metabolism
alpha-Macroglobulins / metabolism

Substances

Biomarkers
Plasminogen Activator Inhibitor 1
Protein C
alpha-Macroglobulins
Antithrombin III
Plasminogen
Tissue Plasminogen Activator