Studies on the reactivity of a tertiary allylic alcohol in an acetophenonic series, a model for natural products synthesis

J Pharm Pharmacol. 2001 Jul;53(7):955-8. doi: 10.1211/0022357011776379.

Abstract

The synthesis of benzopyranic simplified analogues of dibenzopyranic natural compounds is described, together with the access to a precursor of a new furobenzopyranic natural product. These natural products have anti-cancer activity. The 1,3-diacetoxy-2-acetyl-4-(3-hydroxy-3-methylbut-1-enyl)benzene synthone is used as a common precursor to these structures.

MeSH terms

  • Acetophenones / chemical synthesis*
  • Alcohols / chemistry*
  • Allyl Compounds / chemical synthesis*
  • Benzopyrans / chemical synthesis*
  • Biological Products / chemical synthesis*
  • Biological Products / chemistry
  • Calophyllum / chemistry

Substances

  • Acetophenones
  • Alcohols
  • Allyl Compounds
  • Benzopyrans
  • Biological Products
  • acetophenone