Structural characterization of a pentadienyl radical intermediate formed during catalysis by prostaglandin H synthase-2

J Am Chem Soc. 2001 Apr 18;123(15):3609-10. doi: 10.1021/ja015599x.
No abstract available

Publication types

  • Letter

MeSH terms

  • Anti-Inflammatory Agents, Non-Steroidal / chemical synthesis
  • Anti-Inflammatory Agents, Non-Steroidal / chemistry
  • Anti-Inflammatory Agents, Non-Steroidal / pharmacology
  • Catalysis
  • Cyclooxygenase 2
  • Electron Spin Resonance Spectroscopy
  • Isoenzymes / chemistry
  • Isoenzymes / metabolism*
  • Molecular Conformation
  • Prostaglandin H2
  • Prostaglandin-Endoperoxide Synthases / chemistry
  • Prostaglandin-Endoperoxide Synthases / metabolism*
  • Prostaglandins G / chemical synthesis
  • Prostaglandins G / chemistry*
  • Prostaglandins H / biosynthesis
  • Prostaglandins H / chemistry
  • Structure-Activity Relationship

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Isoenzymes
  • Prostaglandins G
  • Prostaglandins H
  • Prostaglandin H2
  • prostaglandin G2
  • Cyclooxygenase 2
  • Prostaglandin-Endoperoxide Synthases