Abstract
We report on a 49 year old female with primary extra-medullary manifestation of a acute myeloid leukemia in the lungs without leukemic signs. The disease was diagnosed by detection of leukemic blast cells in bronchoalveolar lavage. Chemotherapy with the TAD-VP-scheme resulted in partial remission. The patient died in systemic early relapse. To our knowledge this is the first description of primary isolated extra-medullary manifestation of a acute myeloid leukemia in the lungs.
MeSH terms
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use
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Blast Crisis / pathology
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Bronchoalveolar Lavage Fluid / cytology*
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Cytarabine / administration & dosage
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Daunorubicin / administration & dosage
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Female
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Humans
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Leukemia, Myeloid, Acute / diagnostic imaging
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Leukemia, Myeloid, Acute / drug therapy
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Leukemia, Myeloid, Acute / pathology*
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Lung Neoplasms / diagnostic imaging
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Lung Neoplasms / drug therapy
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Lung Neoplasms / pathology*
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Middle Aged
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Prednisolone / administration & dosage
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Radiography
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Thioguanine / administration & dosage
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Vincristine / administration & dosage
Substances
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Cytarabine
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Vincristine
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Prednisolone
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Thioguanine
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Daunorubicin