Abstract
This article represents the proceedings of a symposium at the 2000 ISBRA Meeting in Yokohama, Japan. The chairs were Helmut K. Seitz and Shohei Matsuzaki. The presentations were (1) Alcohol dehydrogenase-2 and aldehyde dehydrogenase-2 genotype and cancer risk for upper aerodigestive tract in Japanese alcoholics, by Akira Yokoyama; (2) The role of acetaldehyde in alcohol-associated carcinogenesis, by Nils Homann; (3) High salivary acetaldehyde levels after a moderate dose of alcohol in ALDH2-deficient subjects, by Satu Väkeväinen; (4) Alcohol and vitamin A interactions, by Xian Dong Wang; and (5) Alcohol and colorectal cancer, by Helmut K. Seitz.
MeSH terms
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Acetaldehyde / metabolism*
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Alcohol Dehydrogenase / genetics
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Alcohol Dehydrogenase / metabolism
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Alcoholism / genetics
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Alcoholism / metabolism*
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Aldehyde Dehydrogenase / genetics
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Aldehyde Dehydrogenase / metabolism*
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Aldehyde Dehydrogenase, Mitochondrial
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Animals
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Central Nervous System Depressants / metabolism
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Central Nervous System Depressants / pharmacology
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Colorectal Neoplasms / etiology
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Colorectal Neoplasms / metabolism*
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Cytochrome P-450 CYP2E1 / drug effects
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Cytochrome P-450 CYP2E1 / metabolism
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Ethanol / metabolism
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Ethanol / pharmacology
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Head and Neck Neoplasms / genetics
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Head and Neck Neoplasms / metabolism*
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Humans
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Male
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Polymorphism, Genetic / genetics
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Risk Factors
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Saliva / drug effects
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Saliva / metabolism
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Vitamin A / metabolism*
Substances
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Central Nervous System Depressants
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Vitamin A
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Ethanol
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Alcohol Dehydrogenase
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Cytochrome P-450 CYP2E1
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ALDH2 protein, human
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Aldehyde Dehydrogenase
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Aldehyde Dehydrogenase, Mitochondrial
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Acetaldehyde